The best way to clean your mattress is to start by vacuuming it thoroughly, then spot-treat any stains with a mixture of water and mild detergent. After that, sprinkle baking soda over the entire surface and let it sit for a few hours to absorb any odors. Finally, vacuum up the baking soda and flip the mattress over to repeat the process on the other side. Regular cleaning of your mattress can help you sleep better and breathe easier, so it's worth taking the time to do it right.